Search on: 2-HYDROXY-5-NITROBENZYL BROMIDE 
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Descriptor English:   2-Hydroxy-5-nitrobenzyl Bromide 
Descriptor Spanish:   2-Hidroxi-5-nitrobencil Bromuro 
Descriptor Portuguese:   2-Hidroxi-5-nitrobenzil Brometo 
Synonyms English:   Koshland's Reagent I  
Tree Number:   D02.455.426.559.389.140.400
D02.640.743.400
D02.755.566.400
Definition English:   A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent. 
Indexing Annotation English:   D25-26 qualif
Pharmacological Action:   Indicators and Reagents
 
History Note English:   91(75); was see under NITROPHENOLS 1975-90 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects analysis
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use  
Record Number:   7076 
Unique Identifier:   D015077 

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